I am Bren Professor of Computational Biology at Caltech. The purpose of this site is to supplement my academic website with updates on my research and teaching activities, along with reviews and commentary on current topics in computational biology.
I ask that all submitted comments include a valid email address in the appropriate box (addresses can be anonymized, e.g. iamnotme@google.com but must work so that I can respond directly to the commenter if needed). I reserve the right to reject comments if they contain inappropriate content.
“Socrates:…neither poetry nor prose, spoken or written, is of any great value, if, like the compositions of the rhapsodes, they are only recited in order to be believed, and not with any view to criticism or instruction”
=== Site Notes ===
The WordPress theme I use is Tarski. I selected it based on its use by Terence Tao for his What’s new blog. The header image is a photograph I took of the sculpture Dansleikur by Icelandic sculptor Þorbjörg Pálsdóttir.
=== Copyright ===
Please feel free to link to any of the material in this blog. Text from the posts, images, pdf attachments and keynote presentations may be reproduced if properly cited (reference to URL, or paper if appropriate).
9 comments
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April 21, 2014 at 3:47 pm
FamilyDoc2
Do comments that challenge your blog posts always get deleted? I inquire about your credentials and the response is to remove my comment. Not exactly scientific inquiry and discussion, is it?
April 21, 2014 at 3:52 pm
Lior Pachter
I’m sorry, I have no idea what you are talking about. Your comment on my blog was posted on the thread of my most recent post “Does researching casual marijuana use cause brain abnormalities” where you submitted it. In fact, I replied to your inquiry right away and posted links to my CV and website on that thread; several other bloggers also replied to you. I would like to point out that this “About” page has always had a link to my personal website that includes a list of my publications and my CV. I did delete a second identical copy of your original submission as I assumed you had double-posted in error. I hope that clears up the misunderstanding.
July 6, 2014 at 12:31 pm
Riley
It will be extremely helpful to hear about your comment on this work on your blog: http://www.cell.com/cell/abstract/S0092-8674(14)00720-X
September 25, 2014 at 5:11 am
Bruce Turner
I am involved in a challenging project sequencing (genomic) growth hormone genes in some interesting fish species. The introns of many of these contain very long runs of dinucleotide repeats, sometimes punctuated by other sequences. Is there a SMART-seq technique developed to handle these? If so, is it available as a service?
April 5, 2015 at 11:14 pm
Rana Dajani
I totally agree with your ideas proposed in your blog.
I am a biologist and stand in awe of mathematicians.
I am always seeking ways to create collaborations between both fields.
I am an Associate Professor of molecular biology in Jordan.
I wonder how can I help?
Can we write a grant to NSF proposing to explore, foster and build this relationship between disciplines in Jordan?
In Jordan high tech research is not affordable. So mathematical biology is an answer to graduate students because they would only need internet and a very good computer.
Please advise
Rana
April 14, 2016 at 8:14 am
ezparz
After reading your debunking of the Cannabis and Brain morphology study I was wondering if you’d analyze a counter study for its efficacy. Thanks, -Ezra Parzybok, Cannabis Consultant http://www.thehighend.org
hhttp://www.beyondthc.com/wp-content/uploads/2015/11/No-brain-changes-with-Marijuana-use.pdf
Your post: https://liorpachter.wordpress.com/2014/04/17/does-researching-casual-marijuana-use-cause-brain-abnormalities/
May 24, 2018 at 11:28 am
August Ludviksson
Hi Lior,
I think it would be only be fair of you to mention that the banner of your blog shows a sculpture by the Icelandic artist Þorbjörg Pálsdóttir. The title of the sculpture is “Dansleikur” (“Dance”).
Thank you for your blog posts.
Best regards,
August
May 24, 2018 at 7:13 pm
Lior Pachter
Thanks for your comment. That’s a good point and I’ve updated the About page to acknowledge the sculptor.
August 9, 2018 at 6:57 am
Francisco Lima
Hi Lior,
Great work, great writing. I came across some GWAS papers that use alpha levels of 1 (?). The authors divide alpha of one by ~100,000 SNPs (Bonferroni-like) and use this as their P-value MHC. I was working on the probability of having at least one false positive for a very large number of tests – it approximates an astounding 0.63. How does this get past reviewing? Maybe something worth covering?
Regards and keep up inspiring scientists,
Francisco